Publications

Scientific Publications

Lectures

Theses

Annual Reports

Fraunhofer facilities do application-oriented research. The information and acquisition of new partners is strongly based on PR work, specifically on Internet platforms.

Documents and quotes are always being updated by the central media service of the Fraunhofer Society.

Search our research & work fields, talks and publication overviews. Studies and expert opinions are prepared to order.

In preparing these, we use Fraunhofer-Publica, the interdisciplinary bibliographical database.

 

Publications 2014


Author Title Publishing house
Dagmar B. Stengel, Rafael Conde-Álvarez,SolèneConnan, Udo Nitschke, Francisco Arenas, Helena Abreu, José Bonomi Barufi, Fungyi Chow, Daniel Robledo, Erik-Jan Malta, Mayte Mata, Talina Konotchick,Cristina Nassar, Ángel Pérez-Ruzafa, David López, Ronny Marquardt, FátimaVaz-Pinto, Paula Celis Plá, Maibe Hermoso, Esther Ruiz, Gema Ordoñez, Pauli Flores, Marianela Zanolla, Elena Bañares-España, María Altamirano, Nathalie Korbee, Kai Bischof, Félix L. Figueroa Short-term effect of CO2, nutrients and temperature on three marine macroalgae under solar radiation. Aquatic Biology - 2014 - doi: 10.3354/ab00576
Mehnert JM, Kisch T, Brandenburger M. Co-culture systems of human sweat gland derived stem cells and peripheral nerve cells: an in vitro approach for peripheral nerve regeneration Cell Physiol Biochem 2014;34(4):1027-37. doi: 10.1159/000366318
Rakers S, Imse F, Gebert M Real-time cell analysis: sensitivity of different vertebrate cell cultures to copper sulfate measured by xCELLigence® Ecotoxicology, 23:1582-1591, DOI 10.1007/s10646-014-1279-6
Gebert M., Lüllwitz L., Grunow B. Neue Rohstoffe aus dem Bioreaktor FOOD Lab

Publications 2013


Author Title Publishing house
Becker T., Schultz S., Rapoport D. H., Madany A. Combining Phase Contrast and Immunofluorescence, April 7-11, Images using Geometric Hashing Proceedings of the 10th International Symposium on Biomedical Imaging, pp. 894-897
Mehnert J. M., Brandenburger M., Grunow B. Electrophysiological Characterization of Spontaneously Contracting Cell Aggregates Obtained from Rainbow Trout Larvae with Multielectrode Arrays Cell Physiol Biochem. 2013;32(5):1374-85
Wehner S., Dörrich A. K., Ciba P., Wilde A., Marz M. pRNA: NoRC associated RNA of rRNA operons RNA Biol. 2013 Dec 20;11(1). [Epub ahead of print]
Rakers S. Editorial Recent impulses to marine science and engineering- from coast to deep sea: multiscale approaches to marine sciences; eds M.H. Einsporn, J. Wiedling, S. Beilfuss, DGM publishing company, Germany
Gebert M., Luellwitz L. How to integrate blue biotechnology in food industry and medicine Recent impulses to marine science and engineering- from coast to deep sea: multiscale approaches to marine sciences; eds M.H. Einsporn, J. Wiedling, S. Beilfuss, DGM publishing company, Germany
Danner S., Benzin H., Vollbrandt T., Oder J., Richter A., Kruse C. Quantum Dots Do Not Alter the Differentiation Potential of Pancreatic Stem Cells and Are Distributed Randomly among Daughter Cells International Journal of Cell Biology, vol. 2013, Article ID 918242
Richter A., Xie Y., Schumacher A., Loeffler S., Kirch, Al-Hasani J., Rapoport D. H., Kruse C., Moser A., Tronnier V., Danner S., Hofmann U. G. A simple implantation method for flexible, multisite microelectrodes into rat brains Front Neuroeng 2013; 6:6
Richter A., Nissen N., Mailänder P., Stang F., Siemers F., Kruse C., Danner S. Mammary gland-derived nestin+ cell populations can be isolated from human male and female donors Stem Cell Res Ther. 2013 Jul 8;4(4):78
Rakers S., Niklasson L., Steinhagen D., Kruse C., Schauber J., Sundell K., Paus R. Antimicrobial peptides (AMPs) from fish epidermis: Perspectives for investigative dermatology Journal of Investigative Dermatology (JID)133, 1140-1149, doi:10.1038/jid.2012.503

Publications 2012


Author Title Publishing house
Stender B., Brandenburger M., Wang B., Zhang, Z., Schlaefer A. Motion compensation of optical mapping signals from rat heart slices
Rakers S. Tools and techniques in Aquatic Sciences: From fish models to environmental approaches YOUMARES 3 Conference book: 77-79
Hunter D., Anand-Ivell R., Danner S., Ivell R. Models of in vitro spermatogenisis Spermatogenesis, 2012 Jan 1; (1):32-43
Grunow B., Schmidt M., Klinger M., Kruse C. Development of an in vitro cultivated, spontaneously and long-term contracting 3D heart model as a robust test system Cell Science and Therapy 3:116. Doi:10.4172/2157-7013.1000116
Gebert M. Analysis of cell powder from in vitro cultured fish cells Perspectives from the Submariner Blue Biotech Cooperation Event
Becker T., Madany A. Morphology-based features for adaptive mitosis detection of in vitro stem cell tracking data Methods of Information in Medicine, 51: 449–456, 2012. doi: 10.3414/ME11-02-0038.
Nazirizadeh Y., Becker T., Reverey J., Selhuber-Unkel C., Rapoport D. H., Gerken M. Photonic crystal slabs for surface contrast enhancement in microscopy of transparent objects Optics Express, vol. 20, pp. 14451-14459,
Becker T., Rapoport D., Madany-Mamlouk A. From Timelapse-Data to Genealogic Trees: Using Different Contrast Mechanisms to Improve Cell Tracking Proceedings of the 9th International Symposium on Biomedical Imaging, 2-5 May, pp. 386-389
Klimach P., Richter A., Danner S., Kruse C.,Tronnier V., Hofmann U. G. Automated image analysis of immunohistochemical stained brain slices of long term polyimid brain implants Biomed Tech (Berl.), DOI: 10.1515/bmt-2012-4179
Bünger S., Barow M., Thorns C., Freitag-Wolf S., Danner S., Tiede S., Pries R., Görg S., Bruch H. P., Roblick U. J., Kruse C., Habermann J. K. Pancreatic Carcinoma Cell Lines Reflect Frequency and Variability of Cancer Stem Cell Markers in Clinical Tissue Eur Surg Res, Aug 30;49(2):88-98
Danner S., Kremer M., Petschnik A. E., Nagel S., Zhang Z., Hopfner U., Reckhenrich A. K., Weber C., Schenk T. L., Becker T., Kruse C., Machens H. G., Egana J. T. The Use of Human Sweat Gland-derived Stem Cells for Enhancing Vascularization during Dermal Regeneration Journal of Investigative Dermatology 2012 Jun; 132 (6):1707-16.doi: 10.1038/jid.2012.31. Epub 2012 Mar 1. PubMed PMID: 22377762

Publications 2011


Author Title Publishing house
Voigt M., Rapoport D. H., Kruse C. Adherent cells grow at different rates on spherical microcarriers of different size
Frahm S., Kruse C., Rapoport D. H. Comparison of cell populations from salivary glands obtained by different preperaton procedures Abstracts of the World Conference on Regenerative Medicine, volume 6, page 200, Leipzig, Germany
Gebert M., Kirchhof J., Rakers S. and Kruse C. Novel molecular tools for gene and protein analysis of fish DGM YouMaRes 2.0 Conference Proceedings: 74
Becker T., Rapoport D. H., Madany Mamlouk A. and Maas R. An agent-based framework to simulate cell cell communication of adult stem cell populations in vitro. Abstracts of the World Conference on Regenerative Medicine, volume 6, page 378, Leipzig, Germany
Becker T., Madany Mamlouk A. Automated morphology-based mitosis detection in stem cell cultures using phase contrast microscopy In Proceedings 2011 World Congress on Engineering and Technology, volume 7, pages 523–526. IEEE Press
Rapoport D. H., Becker T., Madany Mamlouk A., Schicktanz S., Kruse C. A novel validation algorithm allows for automated cell tracking and the extraction of biologically meaningful parameters PLoS ONE. 2011 Nov;6(11):e27315
Müller F. J., Schuldt B.M., Williams R., Mason D., Altun G., Papapetrou E. P., Danner S., Goldmann J. E., Herbst A., Schmidt N. O., Aldenhoff J. B., Laurent L. C., Loring J. F. A bioinformatic assay for pluripotency in human cells Nat Methods. 2011 Apr;8(4):315-7
Ziyang Zhang, Wulf D. Ito, Ursula Hopfner, Björn Böhmert, Mathias, Kremer, Ann K. Reckhenrich,Yves Harder, Natalie Lund, Charli Kruse, Hans-Günther Machens, J. Tomás Egaña The Role of Single Cell Derived Vascular Resident Endothelial Progenitor Cells in the Enhancement of Vascularization in Scaffold-based Skin Regeneration Biomaterials 2011 Jun;32(17):4109-17
Becker T., Rapoport H. D., Madany Mamlouk A. Adaptive Mitosis Detection in Large in vitro Stem Cell Populations using Timelapse Microscopy Proc. Bildverabeitung für die Medizin (BVM), Luebeck, Germany, Informatik aktuell, pp. 49-53, 2011
Rakers S., Klinger M., Kruse C., Gebert M. Pros and cons of fish skin cells in culture: Long-term full skin and short-term scale cell culture from rainbow trout, Oncorhynchus mykiss European Journal of Cell Biology, 2011 Dec;90(12):1041-51. doi:10.1016/j.ejcb.2011.08.003
Rakers S., Kruse C., Gebert, M. Fish cells - a source for new technologies?! DGM YouMaRes 2.0 Conference Proceedings: 75
Ciba P., Lermen D., Fuhr G. R., Kruse C. Organization and implementation of a modern biobank (“CRYO-BREHM“): current and future applications for cryoconserved wildlife cell cultures Biopreservation and Biobanking. September 2011, 9(3): 289-313
Langner S., Rakers S., Ciba P., Petschnik A. E., Rapoport D.H., Kruse C. New cell line from adipopancreatic tissue of Atlantic herring Clupea harengus. Aquatic Biology, Vol. 11: 271–278, 2011, doi: 10.3354/ab00317
Grunow B., Wenzel J., Terlau H., Langner S., Gebert M., Kruse C. In vitro developed spontaneously contracting cardiomyocytes from rainbow trout as a model system for human heart research. Cellular Physiology and Biochemistry (2011) 27, 01-12
Richter A., Kruse C., Moser A., Hofmann U. G., and Danner S. Cellular modulation of polymeric device surfaces: promise of adult stem cells for neuroprosthetics. Frontiers in Neuroscience (2011) 5:114, doi: 10.3389/fnins.2011.00114
Richter A., Kühn N., Danner S., Kruse C. Organotypic brain slice cultures can be used to simulate transplantation studies in vitro Biomed Tech 2011; 56 (Suppl. 1), DOI: 10.1515/BMT.2011.694
Petschnik A. E., Fell B., Tiede S., Habermann J. K., Pries R., Kruse C., Danner S. A novel xenogeneic co-culture system to examine neuronal differentiation capability of various adult human stem cells PLoS One, 2011;6(9):e24944
Grunow B., Noglick S., Kruse C., Gebert M. Isolation of Cells from Atlantic Sturgeon (Acipenser oxyrinchus oxyrinchus) and Optimization of Culture Conditions Aquatic Biology, DOI 10.3354/ab0383
Richter A., Kruse C., Moser A., Hofmann U. G. and Danner S. Next-generation deep brain stimulating devices with neuropil-mimicking cell cover Regenerative Medicine 6, 463, ISSN 1746-0751

Publications 2010


Author Title Publishing house
Ernst N., Tiede S., Tronnier V., Kruse C., Zechel C., Paus R. An improved, standardised protocol for the isolation, enrichment and targeted neural differentiation of Nestin+ progenitors from adult human dermis
Rakers S., Gebert M., Uppalapati S., Meyer W., Maderson P., Sell A., Kruse C., Paus R. “Fishy matters”: The relevance of fish skin biology to investigative dermatology Experimental Dermatology, 2010, Apr;19(4):313-24. DOI:10.1111/j.1600-0625.2009.01059.x
Grunow B., Wenzel J., Gebert M., Kruse C. In vitro generated autonomously contracting cardiomyocytes from rainbow trout as a model system for human heart research. Journal of Biotechnology (2010) 150 (1), 6-7
Grunow B., Ciba P., Rakers S., Klinger M., Anders E., Kruse C. In vitro expansion of autonomously contracting, cardiomyogenic structures from rainbow trout, Oncorhynchus mykiss. Journal of fish biology (2010) 76, 427-434
Ciba P., Hering-Hagenbeck S., Nagel U., Kruse C. Untersuchung und Archivierung von Stammzellen aus Wildtieren; hier: Schneeleopard (Uncia uncia) und Rothschildgiraffe (Giraffa camelopardalis rothschildi). Der Zoologische Garten. 10.1016/j.zoolgart.2010.08.001
Richter A., Kruse C., Hofmann U.G., Danner S. Applying controlled shear stress on cell covered microprobes Biomedizinische Technik/Biomedical Engineering - de Gruyter (2010) 55, 4, ISSN: 0939-4990
Petschnik A. E., Fell B., Klatte J. E., Evers L. H., Kruse C., Danner S. Humane Schweißdrüsen: eine viel versprechende Quelle für Nestin-positive Stammzellen Regenerative Medizin, 3. Jahrgang, Heft 1, S. 8-9
Petschnik A. E, Fell B., Kruse C., Danner S. The role of alpha-smooth muscle actin in myogenic differentiation of human glandular stem cells and their potential for smooth muscle cell replacement therapies Expert Opin Biol Ther, Jun;10(6):853-61
Petschnik A. E., Klatte J. E., Evers L. H., Kruse C., Paus R., Danner S. Phenotypic indications that human sweat glands are a rich source of nestin-positive stem cell populations Br J Dermatol, 162(2):380-3
Luellwitz L., Hoffmann D., Grunow B., Noglick S., Gebert M., Kruse C. A novel fish cell line converts n-3 polyunsaturated fatty acids into n-3 highly unsaturated fatty acids in vitro Abstracts of the First International Marine Ingredients Conference Oslo, Oslo, Norway

Publications 2009


Author Title Publishing house
Ciba P., Danner S. Neue Haut aus Stammzellen
Salem H., Ciba P., Rapoport D. H., Egana J. T., Reithmayer K., Kadry M., Machens H. G., Kruse C. The influence of pancreas-derived stem cells on scaffold based skin regeneration Biomaterials, 2009 Feb;30(5):789-96
Grunow B., Gebert M., Kruse C. Heart Regeneration versus Heart Development. Regenerative Medicine, Nov 4 (6), 187 2
Richter A., Loeffler S., Moser A., Kruse C., Hofmann U., Danner S. Improvement of neural prosthetic devices using adult pancreatic stem cells Biomaterialien (2009) 10, 104; ISSN:1616-0177
Richter A., Kruse C., Hofmann U., and Danner S. Cell-based improvement of neural prosthetic device - BioStar 2008–Science in Exchange Meeting Abstracts Tissue Engineering Part A (2009) 15, 675-737, DOI:10.1089/ten.tea.2009.1500
Petschnik A. E., Ciba P., Kruse C., Danner S. Controlling alpha-SMA expression in adult human pancreatic stem cells by soluble factors Ann Anat, 191, 116-125
Egana J. T., Danner S., Kremer M., Rapoport D. H., Lohmeyer J. A., Dye J. F., Hopfner U., Lavandero S., Kruse C., Machens H. G. The use of glandular-derived stem cells to improve vascularization in scaffold-mediated dermal regeneration Biomaterials 30:446-58
Lermen D., Blömeke B., Browne R., Clarke A., Dyce P. W., Fixemer T., Fuhr G.R., Holt W. V., Jewgenow K., Llloyd R.E., Lötters S., Paulus M., Reid G., Rapoport D. H., Rawson D., Ringleb J., Ryder O. A., Spörl G., Schmitt T., Veith M., Müller P. Cryobanking of viable biomaterials: implementation of new strategies for Conservation purposes Molecular Ecology; 18, 1030-1033

Publications 2008


Author Title Publishing house
Ciba P., Sturmheit T. M., Petschnik A. E., Kruse C., Danner S. In vitro cultures of human pancreatic stem cells: Gene and protein expression of designated markers varies with passage
Kruse C., Danner S., Rapoport D. H., Current Stem Cell Technology: Limitations and Realistic Expectations Eng. Life Sci.
Ciba, P., Schicktanz, S., Anders, E., Siegl, E., Stielow, A., Klink, E., Kruse, C. Long-Term Culture of a Cell Population from Siberian Sturgeon (Acipenser Baerii) Head Kidney. Fish Physiology and Biochemistry,Vol 34, Number 4 (2008), 367-372; IF: 0,505
Kruse, C., Danner, S., Rapoport, D. Current Stem Cell Technology: Limitations and Realistic Expectations. Eng.Life Sci. 8, No. 1, 13–18 (2008)
Kajahn, J., Gorjup, E., Tiede, S., v. Briesen, H., Paus, R., Kruse, C and Danner, S. Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. Eur. J. Cell Biol. (2008) 87:39-46. Epub 2007 Sep 1

Publications 2007


Author Title Publishing house
Ciba P., Schicktanz S., Anders E., Siegl E., Stielow A., Klink E., Kruse C. Long-term culture of a cell population from Siberian sturgeon (Acipenser baerii ) head kidney.
Danner, S., Kajahn, J., Geismann, C., Klink, E. and Kruse, C. Derivation of oocyte-like cells from a clonal pancreatic stem cell line. Mol. Hum. Reprod, (2007); 13:11-20. Epub 2006 Nov 17
Tiede, S., Kloepper, J.E., Bodò, E, Tiwari, S., Kruse, C. and Paus, R. Hair follicle stem cells: Walking the maze. Eur. J. Cell Biol. (2007) 86:355-376. Epub 2007 Jun 18
Hilgendorf, I., Aßmuth, K., Sparmann, G.,Emmrich, J. and Kruse, C. Enhanced vigilin and anionic trypsinogen expression in experimental chronic pancreatitis. Centr. Eur. J. Med . (2007) 2:159-167

Publications 2006


Author Title Publishing house
Kruse C., Bodó E., Petschnik A. E., Danner S., Tiede S., Paus R. Towards the development of a pragmatic technique for isolating and differentiating nestin-positive cells from human scalp skin into neuronal and glial cell populations: generating neurons from human skin?
Kruse C., Kajahn J., Petschnik A. E., Maass A., Klink E., Rapoport D. H., Wedel T. Adult pancreatic stem/progenitor cells spontaneously differentiate in vitro into multiple cell lineages and form teratoma-like structures Ann Anat, 188, 503-517
Guldner N. W., Kajahn J., Klinger M., Sievers H.-H., Kruse, C. Autonomously contracting human cardiomyocytes generated from adult pancreatic stem cells and enhanced in cocultures with myocardial biopsies. Artif. Org. 29 (2006), 1158-1166
Kruse C., Klink E., Kajahn J., Wedel T., Danner S. Pancreatic stem cells form multicellular teratoma-like structures in vitro. Cytotherapy 8 (2006), 50
Danner S. and Kruse C. Clonal analysis of long-term cultures from pancreatic stem cells. Cytotherapy 8 (2006), 50
Kajahn J., Ciba P., Klinger M., Kruse C., Guldner N. W. Human cardiomyogenic cells generated from adult human pancreatic stem cells. Cytotherapy 8 (2006), 50
Kruse C. Möglichkeiten und Grenzen der Stammzelltherapie. in: „Technische Systeme für Biotechnologie und Umwelt“, 9-12, Hrsg.: Dieter Beckmann und Manfred Meister; ISBN-10: 3-00-018621-2 (2006)

Publications 2005


Author Title Publishing house
Kramer, J., Klinger, M., Kruse, C., Faza, M., Hargus, G., Rohwedel, J. Ultrastructural analysis of mouse embryonic stem cell-derived chondrocytes.
Maass, A., Rohwedel, J., Wedel, T. and Kruse, C. Characterization of adult stem cells derived from rat pancreas. Int. J. Artif. Organs 28 (2005), 397

Publications 2004


Author Title Publishing house
Vollbrandt, T., Willkomm, D., Stoßberg, H., and Kruse, C. Vigilin is colocalized with 80S ribosomes and binds to the ribosomal complex through its C-terminal domain.
Kruse, C., Birth, M., Rohwedel, J., Assmuth, K., Goepel, A., and Wedel, T. Pluripotency of adult stem cells derived from human and rat pancreas. Appl. Phys. A 79 (2004), 1617-1624