Project "KHV-Vacc"

Background: In many regions of Germany carp farming  suffers significantly from the Koi Herpesvirus-Infection (KHV-I), caused by an infection of carp with the Cyprinid Herpesvirus (CyHV-3, also known as Koi Herpesvirus (KHV)). Outbreaks of KHV-I can generate high economic losses caused by mortalities, costs for killing contagious and infected fish, disinfection of affected ponds and missing income from carp farming. The economic basis of affected plants can be burdened up to termination of business. Up to now no effective measures of prevention and therapy for this disease are available. For this reason, efficient instruments of monitoring to contain this viral disease are required.

Aim of this project: To contain this disease in endemic areas and to protect healthy carp stocks from infection, an improvement of diagnostic methods and a development of preventive measures are required. With the KHV-Vacc project an improvement of diagnostics of CyHV-3 through cell culture as well as the development of new vaccines (including adjuvants) shall be achieved. This way we can effectively prevent losses and distinguish vaccinated populations and stocks with latent infections.

 

Cooperation partner: 

Fraunhofer Research Institution for Marine Biotechnology and Cell Technology (EMB)

Friedrich-Alexander University Erlangen (FAU)

University of Veterinary Medicine Hannover (TiHo)

Friedrich-Löffler Institute Insel Riems (FLI)

 

Funded by: Federal Ministry of Food and Agriculture (BMEL)

Period/duration: 01.10.2015 - 30.09.2018

 

Further Information:

 

https://www.fraunhofer.de/en/press/research-news/2018/March/defying-the-koi-herpes-virus.html