Fraunhofer-Entwicklungszentrum für Marine und Zelluläre Biotechnologie
Fraunhofer-Entwicklungszentrum für Marine und Zelluläre Biotechnologie

Wissenschaftliche Publikationen

Publikationen 2021#

Autor Titel Verlag
Krüger, K., Böhme, E., Klettner, A. K., Zille, M. The potential of marine resources for retinal diseases: a systematic review of the molecular mechanisms Taylor & Francis online, https://doi.org/10.1080/10408398.2021.191524
Jana Van Dycke, J., Cuvry, A., Knickmann, J., Ny, A., Rahers, S., Tauber, S., de Witte, P., Neyts, J., Rocha-Pereira, J. Infection of zebrafish larvae with human norovirus and evaluation of the in vivo efficacy of small molecule inhibitors PLoS Pathog. 2019 Sep 19;15(9):e1008009. doi: 10.1371/journal.ppat.1008009. Takaki et al., Nature Protocols 8, 1114–1124 (2013) doi:10.1038/nprot.2013.068
Rebl H., Bergemann, C., Rakers, S., Nebe, B., Rebl, A. Plasma Treatment of Fish Cells: The Importance of Defining
Cell Culture Conditions in Comparative Studies		 Appl. Sci. 2021, 11, 2534. https://
doi.org/10.3390/app11062534

 

Publikationen 2020#

Autor Titel Verlag
Kruse, C. Marine Bioökonomie. Buchbeitrag in "Das System Bioökonomie" (Buchbeitrag) Springer-Verlag GmbH D, ein Teil von Springer Nature 2020, D. Thrän, U. Moesenfechtel (Hrsg.) https://doi.org/10.1007/978-3-662-60730-5_7

Publikationen 2019#

Autor Titel Verlag
Brandenburger M., Kruse C. Fabrication of a Co-Culture System with Human Sweat Gland-Derived Cells and Peripheral Nerve Cells Methods Mol Biol. 2019;1993:139-148. doi: 10.1007/978-1-4939-9473-1_11.
Brandenburger M, Kruse C Heterogeneity of Sweat Gland Stem Cells Adv Exp Med Biol. 2019;1169:55-62. doi: 10.1007/978-3-030-24108-7_3. Review
Kolbe I, Leinweber B, Brandenburger M, Oster H. Circadian clock network desynchrony promotes weight gain and alters glucose homeostasis in mice. Mol Metab. 2019 Dec;30:140-151. doi: 10.1016/j.molmet.2019.09.012. Epub 2019 Oct 8.
M. Zvolsky, N. Schreiner, S. Seeger, M. Schaar, S. Rakers, and M. Rafecas Digital Zebrafish Phantom based on Micro-CT Data Paper NSSMIC Konferenz
Ikhsan M, Palumbo A, Rose D, Zille M, Boltze J Neuronal Stem Cell-Drug Interactions: A Systematic Review and Meta-Analysis Stem Cells Transl Med. 2019 Jul 16. doi: 10.1002/sctm.19-0020. [Epub ahead of print] Review. PMID: 31313515
Castillo X, Castro-Obregón S, Gutiérrez-Becker B, Gutiérrez-Ospina G, Karalis N, Khalil AA, Lopez-Noguerola JS, Rodríguez LL, Martínez-Martínez E, Perez-Cruz C, Pérez-Velázquez J, Piña AL, Rubio K, García HPS, Syeda T, Vanoye-Carlo A, Villringer A, Winek K, Zille M.  Re-thinking the Etiological Framework of Neurodegeneration Front Neurosci. 2019 Jul 24;13:728. doi:10.3389/fnins.2019.00728. eCollection 2019. Review. PMID: 31396030
Gebert, M.  Fischzucht und Gentechnik: Grundlagen, Anwendungsgebiete und Potenziale Ernährung in Fokus (02/2019) , Herausgeber BZfE
Liao T, Lehmann J, Sternstein S, Yay A, Zhang G, Matthießen AE, Schumann S, Siemers F, Kruse C, Hundt JE, Langan EA, Tiede S, Paus R. Nestin(+) progenitor cells isolated from adult human sweat gland stroma promote reepithelialisation and may stimulate angiogenesis in wounded human skin ex vivo Arch Dermatol Res. 2019 May;311(4):325-330. doi: 10.1007/s00403-019-01889-x
Zille M, Kumar A, Kundu N, Bourassa MW, Wong VSC, Willis D, Karuppagounder SS, Ratan RR Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors eNeuro. 2019 Feb 15;6(1). pii: ENEURO.0263-18.2019. doi: 10.1523/ENEURO.0263-18.2019
Krzysztof Rakus, Mikołaj Adamek, Miriam Mojżesz, Piotr Podlasz, Małgorzata Evaluation of zebrafish (Danio rerio) as an animal model for the viral infections of fish. Journal of Fish Diseases, Volume 42, Issue 6, June 2019, Pages 923-934  
     

Publikationen 2018#

Autor                                                                                         TIitel Verlag              
Ballarin, L.; Rinkevich, B.; Bartscherer, K.; Burzynski, A.; Cambier, S.; Cammarata, M.; Domart-Coulon, I.; Drobne, D.; Encinas, J.; Frank, U.; Geneviere, A.-M.; Hobmayer, B.; Löhelaid, H.; Lyons, D.; Martinez, P.; Oliveri, P.; Peric, L.; Piraino, S.; Maristem - Stem Cells of Marine/Aquatic Invertebrates: From Basic Research to Innovative Applications Sustainability 2018, 10, 526; doi: 10.3390/su10020526
Schumann S.; Ciba, P. Auf der heutigen Arche ist es kalt VSAO Journal.  

Kruse, C., Ciba, P.

Die Deutsche Zellbank für Wildtiere als naturkundliche Sammlung”, in: Nicole C. Karafyllis (ed.): Theorien der Lebendsammlung. Pflanzen, Mikroben und Tiere als Biofakte in Genbanken

 Lebenswissenschaften im Dialog, Vol. 25
Rakers S, Ondrusch AK, Gruening M, Adamek M, Moeckel B, Gebert M. Monitoring changing cellular characteristics during the development of a fin cell line from Cyprinus carpio Comp Biochem Physiol B Biochem Mol Biol. 2018 Nov;225:1-12. doi: 10.1016/j.cbpb.2018.06.003
Boltze J, Ferrara F, Hainsworth AH, Bridges LR, Zille M, Lobsien D, Barthel H Lesional and perilesional tissue characterization by automated image processing in a novelgyrencephalic animal model of peracute intracerebral hemorrhage. J Cereb Blood Flow Metab
Modo MM, Jolkkonen J, Zille M, Boltze J Future of Animal Modeling for Poststroke Tissue Repair Stroke May;49(5):1099-1106. doi: 10.1161/STROKEAHA.117.018293. Epub 2018
Brockmann I, Ehrenpfordt J, Sturmheit T, Brandenburger M, Kruse C, Zille M, Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges Stem Cells Int.Mar 25;2018:4623615. doi: 10.1155/2018/4623615. eCollection 2018
Selim M, Hanley D, Broderick J, Keep R, Shoamanesh A, Ziai W, Singh V, Sheth K, Rosenblum M, Palesch Y, Muehlschlegel S, Kersten J, Mendelow DA, Gurol E, Gonzales N, Falcone G, Gregson B, Goldstein J, Zille M, Xi G, Ratan RR, James M, Sansing L, Aronowski Hemorrhagic Stroke Academia Industry (HEADS) Roundtable Participants. Unmet Needs and Challenges in Clinical Research of Intracerebral Hemorrhage Stroke
Selim M, Hanley D, Keep R, Aronowski J, Genstler C, James M, Ratan RR, Sansing L, Youd A, Xi G, Zille M, Broderick J, Goldstein J, Gregson B, Falcone G, Gonzales N, Gurol E, Kersten J, Lewkowicz H, Mendelow DA, Muehlschlegel S, Neuman R, Palesch Y, Rosenb Hemorrhagic Stroke Academia Industry (HEADS) Roundtable Participants. Basic and Translational Research in Intracerebral Hemorrhage: Limitations, Priorities,  and Recommendations Stroke
Rose D, Schmidt A, Brandenburger M, Sturmheit T, Zille M, Boltze J Sulfur mustard skin lesions: A systematic review on pathomechanisms, treatment options and future research directions Toxicol Lett.
Müller B, Boltze J, Czepezauer I, Hesse V; LEGASCREEN Consortium, Wilcke A, Kirsten H. Dyslexia risk variant rs600753 is linked with dyslexia-specific differential allelic expression of DYX1C1 Genet Mol Biol.
Nitzsche B, Boltze J, Ludewig E, Flegel T, Schmidt MJ, Seeger J, Barthel H Brooks OW, Gounis MJ, Stoffel MH, Schulze S A stereotaxic breed-averaged, symmetric T2w canine brain atlas including detailed morphological and volumetrical data sets Neuroimage
     

Publikationen 2017#

Autor                                                                                         TIitel Verlag              
Neef N.E., Müller, B., Liebig J., Schaadt G., Grigutsch M., Gunter T.C., Wilcke A., Kirsten H., Skeide M.A., Kraft I., Kraus N., Emmrich F., Brauer J., Boltze J., Friederici A.D. Dyslexia risk gene relates to representation of sound in the auditory brainstem Dev Cogn Neurosci.
Hainsworth A.H., Allan S.M., Boltze J., Cunningham C., Farris C., Head E., Ihara M., Isaacs J.D., Kalaria R.N., Lesnik-Oberstein S.A.J., Moss M.B., Nitzsche B., Rosenberg G.A., Rutten J.W., Salkovic-Petrisic M., Troen A.M Translational Models for Vascular Cognitive Impairment. A Review Including Larger Species BMC Med. 2017 Jan 25;15(1):16. doi: 10.1186/s12916-017-0793-9.
Koennecke M, Böscke R, Pfannerstill AC, Reers S, Elsner M, Fell B, Richter A, Bruchhage KL, Schumann S, Pries R, Klimek L, Wollenberg B Neuronal Differentiation Capability of Nasal Polyps of Chronic Rhinosinusitis Arch Immunol Ther Exp (Warsz), doi: 10.1007/s00005-017-0456-8. PubMed PMID: 28280847
Balkaya MG, Trueman RC, Boltze J, Corbett D, Jolkkonen J. Behavioral outcome measures to improve experimental
stroke research.		 Behav Brain Res. 2017 Jul 29. pii: S0166-4328(17)30732-5. doi: 10.1016/j.bbr.2017.07.039.  
Boltze J, Ayata C. Challenges and Controversies in Translational Stroke Research - an Introduction Transl Stroke Res. 2016 Oct;7(5):355-7. doi: 10.1007/s12975-016-0492-4
Boltze J, Nitzsche F, Jolkkonen J, Weise G, Pösel C, Nitzsche B,
Wagner DC		 Concise Review: Increasing the Validity of Cerebrovascular Disease Models and Experimental Methods for Translational Stem Cell Research Stem Cells. 35(5):1141-1153. doi: 10.1002/stem.2595
Boltze J, Wagner DC, Barthel H, Gounis MJ Academic-industry Collaborations in Translational Stroke Research. Transl Stroke Res. 2016 Aug;7(4):343-53.
Boltze J, Wagner DC, Henninger N, Plesnila N, Ayata C. Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines Transl Stroke Res. 2016 Aug;7(4):241-7.
Buhrke, F., Borchert, R., Rakers, S. Erste erfolgreiche Befruchtung von Flussbarschlaich mit kryokonservierten Spermien am Standort Born auf dem Darß Fischerei & Fischmarkt in Mecklenburg-Vorpommern 2/2017- 17.Jahrgang, Seiten 37-41
Cui LL, Kinnunen T, Boltze J, Nystedt J, Jolkkonen J. Clumping and Viability of Bone Marrow Derived Mesenchymal
Stromal Cells under Different Preparation Procedures: A Flow Cytometry-Based In Vitro Study		 Stem Cells Int.
2016;2016:1764938
Cui LL, Nitzsche F, Pryazhnikov E, Tibeykina M, Tolppanen L, Rytkönen J, Huhtala T, Mu JW, Khiroug L, Boltze J, Jolkkonen J Integrin a4 Overexpression on Rat Mesenchymal Stem Cells
Enhances Transmigration and Reduces Cerebral Embolism After Intracarotid Injection		 Stroke. 2017 Oct;48(10):2895-
2900.
Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J; ISN&N meeting contributors. Recent progress in translational research on neurovascular and neurodegenerative disorders. Restor Neurol Neurosci. 2017;35(1):87-103.
Diehl R, Ferrara F, Müller C, Dreyer AY, McLeod DD, Fricke S, Boltze J. Immunosuppression for in vivo research: state-ofthe- art protocols and experimental approaches. Cell Mol Immunol. 2017 Feb;14(2):146-179.
Hainsworth AH, Allan SM, Boltze J, Cunningham C, Farris C, Head E, Ihara M, Isaacs JD, Kalaria RN, Lesnik Oberstein SA, Moss MB, Nitzsche B, Rosenberg GA, Rutten JW, Salkovic-Petrisic M, Troen AM. Translational models for vascular cognitive impairment: a review including larger species BMC Med. 2017 Jan 25;15(1):16
Harkness LM, Weckmann M, Kopp M, Becker T, Ashton AW, Burgess JK. Tumstatin regulates the angiogenic and inflammatory potential of airway smooth muscle extracellular matrix. J Cell Mol Med. 2017 Dec;21(12):3288-3297.
Jochimsen TH, Zeisig V, Schulz J, Werner P, Patt M, Patt J, Dreyer AY, Boltze J, Barthel H, Sabri O, Sattler B. Fully automated calculation of image-derived input function in simultaneous PET/MRI in a sheep model. EJNMMI Phys. 2016 Dec;3(1):2.
Jolkkonen J, Mendez-Otero R, de Freitas GR, Boltze J, Rosado-de-Castro PH. The Current State of Cell Therapies for Cerebrovascular Diseases Stem Cells Int. 2016;2016:5215824.
Jovin TG, Albers GW, Liebeskind DS; STAIR IX Consortium Stroke Treatment Academic Industry Roundtable: The Next Generation of Endovascular Trials. Stroke. 2016
Oct;47(10):2656-65
Kraft I, Schreiber J, Cafiero R, Metere R, Schaadt G, Brauer J, Neef NE, Müller B, Kirsten H, Wilcke A, Boltze J, Friederici AD, Skeide MA. Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI Neuroimage. 2016 Dec;143:378-386.
Koennecke M, Böscke R, Pfannerstill AC, Reers S, Elsner M, Fell B, Richter A, Bruchhage KL, Schumann S, Pries R, Klimek L, Wollenberg B. Neuronal Differentiation Capability of Nasal Polyps of Chronic Rhinosinusitis Arch Immunol Ther Exp
(Warsz). 2017
Lees KR, Khatri P; STAIR IX Collaborators. Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke. Stroke. 2016 Aug;47(8):2154-9.
Müller B, Schaadt G, Boltze J, Emmrich F; LEGASCREEN Consortium, Skeide MA, Neef NE, Kraft I, Brauer J, Friederici AD, Kirsten H, Wilcke A. ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR Brain Behav. 2017 Oct 18;7(11):e00851.
Müller B, Wilcke A, Czepezauer I, Ahnert P, Boltze J, Kirsten H; LEGASCREEN consortium Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort Sci Rep.
2016 Jun 17;6:27901
Neef NE, Müller B, Liebig J, Schaadt G, Grigutsch M, Gunter TC, Wilcke A, Kirsten H, Skeide MA, Kraft I, Kraus N, Emmrich F, Brauer J, Boltze J, Friederici AD Dyslexia risk gene relates to representation of sound in the auditory brainstem Dev Cogn Neurosci. 2017 Apr;24:63-71
Nitzsche F, Müller C, Lukomska B, Jolkkonen J, Deten A, Boltze J. Concise Review: MSC Adhesion Cascade-Insights into Homing and Transendothelial Migration Stem Cells. 2017 Jun;35(6):1446-1460
Noguera PA, Grunow B, Klinger M, Lester K, Collet B, Del-Pozo J. Atlantic salmon cardiac primary cultures: An in vitro model to study viral host pathogen interactions and pathogenesis PLoS One. 2017 Jul 20;12(7):e0181058
Nowakowski A, Andrzejewska A, Boltze J, Nitzsche F, Cui LL, Jolkkonen J, Walczak P, Lukomska B, Janowski M. Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells Sci Rep. 2017 Apr
24;7(1):1103.
Peters M, Wielsch B, Boltze J. The role of SUMOylation in cerebral hypoxia and ischemia. Neurochem Int. 2017 Jul;107:66-77.
Puchert M, Pelkner F, Stein G, Angelov DN, Boltze J, Wagner DC, Odoardi F, Flügel A, Streit WJ, Engele J. Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS Mol Cell Neurosci. 2017 Dec; 85:105-118.
Rose D, Schmidt A, Brandenburger M, Sturmheit T, Zille M, Boltze J Sulfur mustard skin lesions: A systematic review on pathomechanisms, treatment options and future research directions Toxicol Lett. 2017 Dec 2. pii: S0378-
4274(17)31500-X.
Skeide MA, Kraft I, Müller B, Schaadt G, Neef NE, Brauer J, Wilcke A, Kirsten H, Boltze J, Friederici AD. NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school. Brain. 2016 Oct;139(Pt 10):2792-
2803.
Weckmann M, Becker T, Nissen G, Pech M, Kopp MV. SiMA: A simplified migration assay for analyzing neutrophil
migration.		 Cytometry A. 2017 Jul;91(7):675-685
Weise G, Pösel C, Möller K, Kranz A, Didwischus N, Boltze J, Wagner DC. High-dosage granulocyte colony stimulating factor treatment alters monocyte trafficking to the brain after experimental stroke Brain Behav Immun. 2017
Feb;60:15-26.
Zerna C, Hill MD, Boltze J. Towards Improved Translational Stroke Research: Progress and Perspectives of the Recent National Institute of Neurological Disorders and Stroke Consensus Group Meeting. Stroke. 2017 Sep;48(9):2341-
2342

Publikationen 2016#

Autor Titel Verlag
Lees K.R., Khatri P., STAIR IX Collaborators. (Boltze J.) Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke Stroke (IF: 5.8)
Diehl R, Ferrara F, Müller C, Dreyer AY, McLeod DD, Fricke S, Boltze J. Immunosuppression for in vivo research: state-of-the-art protocols and experimental approaches Cell Mol Immunol 1/2016
Skeide MA, Kraft I, Müller B, Schaadt G, Neef NE, Brauer J, Wilcke A, Kirsten H, Boltze J, Friederici AD NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school Brain. 2016 Jun 24. pii: aww153
Boltze J, Wagner DC, Barthel H, Gounis MJ Academic-industry Collaborations in Translational Stroke Research Transl Stroke Res. 2016 Jun 14
Boltze J, Wagner DC, Henninger N, Plesnila N, Ayata C Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines Transl Stroke Res. 2016 Jun 14.
Cui LL, Kinnunen T, Boltze J, Nystedt J, Jolkkonen J Clumping and Viability of Bone Marrow Derived Mesenchymal Stromal Cells under Different Preparation Procedures: A Flow Cytometry-Based In Vitro Study Stem Cells Int. 2016;2016:1764938
Pösel C, Möller K, Boltze J, Wagner DC, Weise G. Isolation and Flow Cytometric Analysis of Immune Cells from the Ischemic Mouse Brain J Vis Exp. 2016 Feb 12;(108). doi: 10.3791/53658
Jochimsen TH, Zeisig V, Schulz J, Werner P, Patt M, Patt J, Dreyer AY, Boltze J, Barthel H, Sabri O, Sattler B Fully automated calculation of image-derived input function in simultaneous PET/MRI in a sheep model EJNMMI Phys. 2016 Dec;3(1):2.
Müller B, Wilcke A, Boulesteix AL, Brauer J, Passarge E, Boltze J, Kirsten H Improved prediction of complex diseases by common genetic markers: state of the art and further perspectives Hum Genet. 2016 Mar;135(3):259-72.
Weise G., Pösel C., Möller K., Kranz A., Didwischus N., Boltze J., Wagner D.C High-dosage granulocyte-colony stimulating factor treatment alters inflammatory monocyte activation and brain recruitment after experimental stroke Brain, Behavior and Immunity
Boltze J., Ayata C. Challenges and controversies in translational stroke research - an introduction. Translational Stroke Research
Kraft I., Schreiber J., Cafiero R., Schaadt G., Brauer J., Neef N.E., Müller B., Kirsten H., Wilcke A., Boltze J., Friederici A.D., Michael A. Skeide M.A. Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI Neuroimage
Jolkkonen J., Mendez-Otero R., Rodriguez de Freitas G., Boltze J., Rosado-de-Castro P.H. The Current State of Cell Therapies for Cerebrovascular Diseases Stem Cells International
Jovin TG, Albers GW, Liebeskind DS; STAIR IX Consortium (Boltze J.) Stroke Treatment Academic Industry Roundtable: The Next Generation of Endovascular Trials. Stroke
Müller B., Wilcke A., Czepezauer I, Ahnert P., Boltze J., Kirsten H.; LEGASCREEN consortium Association, characterisation and meta-analysis of SNPs linked to general reading ability
in a German dyslexia case-control cohort		 Sci Rep. 2016
Jun 17;6:27901
Kohn C., Klemens J.M., Kascholke C., Murthy NS., Kohn J.,
Brandenburger M., Hacker MC.		 Dual-component collagenous peptide/reactive oligomer hydrogels as potential
nerve guidance materials - from characterization to functionalization.		 Biomater Sci. 2016 Oct 18;4(11):1605-1621
Schumann S., Benzin H. Zell-Pflaster – Automatisierte Produktion im Bioreaktor labor & more 07.16, S.40-43
     

Publikationen 2015#

Autor Titel Verlag
Labbé C., Chenais N., Depince A., Le Bail P.-Y., Rakers S. Application of somatic cell cryopreservation for biodiversity conservation Cryobiology 71(3):556-557
Möller, K., Pösel, C., Kranz, A., Schulz, I., Scheibe, J., Didwischus, N., Boltze, J., Weise, G., Wagner, D-C. Arterial hypertension aggravates innate immune responses after experimental stroke Front. Cell. Neurosci. doi: 10.3389/fncel.2015.00461
Stieber, R. Neues aus dem Meer GIT Labor-Fachzeitschrift
Ackermann, P.; Hetz, S.; Dieckow, J.; Schicht, M.; Richter, A.; Kruse, C.; Schroeder, I.; Jung, M.; Paulsen, F.P. Isolation and investigation of presumptive murine lacrimal gland stem cells Investigative Ophthalmology & Visual Science, Vol.56, 4350-4363. doi:10.1167/iovs.15-16475
Kisch T, Liodaki E, Kraemer R, Mailaender P, Brandenburger M, Hellwig V, Stang FH. Electrocautery Devices With Feedback Mode and Teflon-Coated Blades Create Less Surgical Smoke for a Quality Improvement in the Operating Theater Medicine
Kisch, T., Weber, C., Rapoport, D. H., Kruse, C., Schumann, S., Strang, F. H., Siemers, F., Matthießen, A. E. LPS-Stimulated Human Skin-derived Stem Cells Enhance Neo-Vascularization during Dermal Regeneration PLoS ONE 10(11): e0142907. doi:10.1371
Schubert, H., Marquardt, R., Schories, D., Blindow, I. Makroalgentaxonomie und –biogeographie an der Universität Rostock heute am Beispiel der Characeenflora Chiles Rostocker Meeresbiolog. Beiträge 26: 34-48.
Rapoport DH, Becker T Cell Technology - Star charts and petri dishes lab&more, 01.15, 20-23
Männel C, Meyer L, Wilcke A, Boltze J, Kirsten H, Friederici AD Working-memory endophenotype and dyslexia-associated genetic variant predict dyslexia phenotype Cortex. 2015 Oct;71:291-305. doi
Nietzsche B., Lobsien D., Geiger K., Barthel H., Zeisig V., Boltze J., Dreyer A. Large Mammals - translational stroke models in sheep ICVD 9th international Congress

Publikationen 2014#


Autor Titel Verlag
Dagmar B. Stengel, Rafael Conde-Álvarez,SolèneConnan, Udo Nitschke, Francisco Arenas, Helena Abreu, José Bonomi Barufi, Fungyi Chow, Daniel Robledo, Erik-Jan Malta, Mayte Mata, Talina Konotchick,Cristina Nassar, Ángel Pérez-Ruzafa, David López, Ronny Marquardt, FátimaVaz-Pinto, Paula Celis Plá, Maibe Hermoso, Esther Ruiz, Gema Ordoñez, Pauli Flores, Marianela Zanolla, Elena Bañares-España, María Altamirano, Nathalie Korbee, Kai Bischof, Félix L. Figueroa Short-term effect of CO2, nutrients and temperature on three marine macroalgae under solar radiation. Aquatic Biology - 2014 - doi: 10.3354/ab00576
Mehnert JM, Kisch T, Brandenburger M. Co-culture systems of human sweat gland derived stem cells and peripheral nerve cells: an in vitro approach for peripheral nerve regeneration Cell Physiol Biochem 2014;34(4):1027-37. doi: 10.1159/000366318
Rakers S, Imse F, Gebert M Real-time cell analysis: sensitivity of different vertebrate cell cultures to copper sulfate measured by xCELLigence® Ecotoxicology, 23:1582-1591, DOI 10.1007/s10646-014-1279-6
Gebert M., Lüllwitz L., Grunow B. Neue Rohstoffe aus dem Bioreaktor FOOD Lab

Publikationen 2013#


Autor Titel Verlag
Becker T., Schultz S., Rapoport D. H., Madany A. Combining Phase Contrast and Immunofluorescence, April 7-11, Images using Geometric Hashing Proceedings of the 10th International Symposium on Biomedical Imaging, pp. 894-897
Mehnert J. M., Brandenburger M., Grunow B. Electrophysiological Characterization of Spontaneously Contracting Cell Aggregates Obtained from Rainbow Trout Larvae with Multielectrode Arrays Cell Physiol Biochem. 2013;32(5):1374-85
Wehner S., Dörrich A. K., Ciba P., Wilde A., Marz M. pRNA: NoRC associated RNA of rRNA operons RNA Biol. 2013 Dec 20;11(1). [Epub ahead of print]
Rakers S. Editorial Recent impulses to marine science and engineering- from coast to deep sea: multiscale approaches to marine sciences; eds M.H. Einsporn, J. Wiedling, S. Beilfuss, DGM publishing company, Germany
Gebert M., Luellwitz L. How to integrate blue biotechnology in food industry and medicine Recent impulses to marine science and engineering- from coast to deep sea: multiscale approaches to marine sciences; eds M.H. Einsporn, J. Wiedling, S. Beilfuss, DGM publishing company, Germany
Danner S., Benzin H., Vollbrandt T., Oder J., Richter A., Kruse C. Quantum Dots Do Not Alter the Differentiation Potential of Pancreatic Stem Cells and Are Distributed Randomly among Daughter Cells International Journal of Cell Biology, vol. 2013, Article ID 918242
Richter A., Xie Y., Schumacher A., Loeffler S., Kirch, Al-Hasani J., Rapoport D. H., Kruse C., Moser A., Tronnier V., Danner S., Hofmann U. G. A simple implantation method for flexible, multisite microelectrodes into rat brains Front Neuroeng 2013; 6:6
Richter A., Nissen N., Mailänder P., Stang F., Siemers F., Kruse C., Danner S. Mammary gland-derived nestin+ cell populations can be isolated from human male and female donors Stem Cell Res Ther. 2013 Jul 8;4(4):78
Rakers S., Niklasson L., Steinhagen D., Kruse C., Schauber J., Sundell K., Paus R. Antimicrobial peptides (AMPs) from fish epidermis: Perspectives for investigative dermatology Journal of Investigative Dermatology (JID)133, 1140-1149, doi:10.1038/jid.2012.503

Publikationen 2012#


Autor Titel Verlag
Stender B., Brandenburger M., Wang B., Zhang, Z., Schlaefer A. Motion compensation of optical mapping signals from rat heart slices Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 855305
Rakers S. Tools and techniques in Aquatic Sciences: From fish models to environmental approaches YOUMARES 3 Conference book: 77-79
Hunter D., Anand-Ivell R., Danner S., Ivell R. Models of in vitro spermatogenisis Spermatogenesis, 2012 Jan 1; (1):32-43
Grunow B., Schmidt M., Klinger M., Kruse C. Development of an in vitro cultivated, spontaneously and long-term contracting 3D heart model as a robust test system Cell Science and Therapy 3:116. Doi:10.4172/2157-7013.1000116
Gebert M. Analysis of cell powder from in vitro cultured fish cells Perspectives from the Submariner Blue Biotech Cooperation Event
Becker T., Madany A. Morphology-based features for adaptive mitosis detection of in vitro stem cell tracking data Methods of Information in Medicine, 51: 449–456, 2012. doi: 10.3414/ME11-02-0038.
Nazirizadeh Y., Becker T., Reverey J., Selhuber-Unkel C., Rapoport D. H., Gerken M. Photonic crystal slabs for surface contrast enhancement in microscopy of transparent objects Optics Express, vol. 20, pp. 14451-14459,
Becker T., Rapoport D., Madany-Mamlouk A. From Timelapse-Data to Genealogic Trees: Using Different Contrast Mechanisms to Improve Cell Tracking Proceedings of the 9th International Symposium on Biomedical Imaging, 2-5 May, pp. 386-389
Klimach P., Richter A., Danner S., Kruse C.,Tronnier V., Hofmann U. G. Automated image analysis of immunohistochemical stained brain slices of long term polyimid brain implants Biomed Tech (Berl.), DOI: 10.1515/bmt-2012-4179
Bünger S., Barow M., Thorns C., Freitag-Wolf S., Danner S., Tiede S., Pries R., Görg S., Bruch H. P., Roblick U. J., Kruse C., Habermann J. K. Pancreatic Carcinoma Cell Lines Reflect Frequency and Variability of Cancer Stem Cell Markers in Clinical Tissue Eur Surg Res, Aug 30;49(2):88-98
Danner S., Kremer M., Petschnik A. E., Nagel S., Zhang Z., Hopfner U., Reckhenrich A. K., Weber C., Schenk T. L., Becker T., Kruse C., Machens H. G., Egana J. T. The Use of Human Sweat Gland-derived Stem Cells for Enhancing Vascularization during Dermal Regeneration Journal of Investigative Dermatology 2012 Jun; 132 (6):1707-16.doi: 10.1038/jid.2012.31. Epub 2012 Mar 1. PubMed PMID: 22377762

Publikationen 2011#


Autor Titel Verlag
Voigt M., Rapoport D. H., Kruse C. Adherent cells grow at different rates on spherical microcarriers of different size Abstracts of the World Conference on Regenerative Medicine, volume 6, page 312, Leipzig, Germany
Frahm S., Kruse C., Rapoport D. H. Comparison of cell populations from salivary glands obtained by different preperaton procedures Abstracts of the World Conference on Regenerative Medicine, volume 6, page 200, Leipzig, Germany
Gebert M., Kirchhof J., Rakers S. and Kruse C. Novel molecular tools for gene and protein analysis of fish DGM YouMaRes 2.0 Conference Proceedings: 74
Becker T., Rapoport D. H., Madany Mamlouk A. and Maas R. An agent-based framework to simulate cell cell communication of adult stem cell populations in vitro. Abstracts of the World Conference on Regenerative Medicine, volume 6, page 378, Leipzig, Germany
Becker T., Madany Mamlouk A. Automated morphology-based mitosis detection in stem cell cultures using phase contrast microscopy In Proceedings 2011 World Congress on Engineering and Technology, volume 7, pages 523–526. IEEE Press
Rapoport D. H., Becker T., Madany Mamlouk A., Schicktanz S., Kruse C. A novel validation algorithm allows for automated cell tracking and the extraction of biologically meaningful parameters PLoS ONE. 2011 Nov;6(11):e27315
Müller F. J., Schuldt B.M., Williams R., Mason D., Altun G., Papapetrou E. P., Danner S., Goldmann J. E., Herbst A., Schmidt N. O., Aldenhoff J. B., Laurent L. C., Loring J. F. A bioinformatic assay for pluripotency in human cells Nat Methods. 2011 Apr;8(4):315-7
Ziyang Zhang, Wulf D. Ito, Ursula Hopfner, Björn Böhmert, Mathias, Kremer, Ann K. Reckhenrich,Yves Harder, Natalie Lund, Charli Kruse, Hans-Günther Machens, J. Tomás Egaña The Role of Single Cell Derived Vascular Resident Endothelial Progenitor Cells in the Enhancement of Vascularization in Scaffold-based Skin Regeneration Biomaterials 2011 Jun;32(17):4109-17
Becker T., Rapoport H. D., Madany Mamlouk A. Adaptive Mitosis Detection in Large in vitro Stem Cell Populations using Timelapse Microscopy Proc. Bildverabeitung für die Medizin (BVM), Luebeck, Germany, Informatik aktuell, pp. 49-53, 2011
Rakers S., Klinger M., Kruse C., Gebert M. Pros and cons of fish skin cells in culture: Long-term full skin and short-term scale cell culture from rainbow trout, Oncorhynchus mykiss European Journal of Cell Biology, 2011 Dec;90(12):1041-51. doi:10.1016/j.ejcb.2011.08.003
Rakers S., Kruse C., Gebert, M. Fish cells - a source for new technologies?! DGM YouMaRes 2.0 Conference Proceedings: 75
Ciba P., Lermen D., Fuhr G. R., Kruse C. Organization and implementation of a modern biobank (“CRYO-BREHM“): current and future applications for cryoconserved wildlife cell cultures Biopreservation and Biobanking. September 2011, 9(3): 289-313
Langner S., Rakers S., Ciba P., Petschnik A. E., Rapoport D.H., Kruse C. New cell line from adipopancreatic tissue of Atlantic herring Clupea harengus. Aquatic Biology, Vol. 11: 271–278, 2011, doi: 10.3354/ab00317
Grunow B., Wenzel J., Terlau H., Langner S., Gebert M., Kruse C. In vitro developed spontaneously contracting cardiomyocytes from rainbow trout as a model system for human heart research. Cellular Physiology and Biochemistry (2011) 27, 01-12
Richter A., Kruse C., Moser A., Hofmann U. G., and Danner S. Cellular modulation of polymeric device surfaces: promise of adult stem cells for neuroprosthetics. Frontiers in Neuroscience (2011) 5:114, doi: 10.3389/fnins.2011.00114
Richter A., Kühn N., Danner S., Kruse C. Organotypic brain slice cultures can be used to simulate transplantation studies in vitro Biomed Tech 2011; 56 (Suppl. 1), DOI: 10.1515/BMT.2011.694
Petschnik A. E., Fell B., Tiede S., Habermann J. K., Pries R., Kruse C., Danner S. A novel xenogeneic co-culture system to examine neuronal differentiation capability of various adult human stem cells PLoS One, 2011;6(9):e24944
Grunow B., Noglick S., Kruse C., Gebert M. Isolation of Cells from Atlantic Sturgeon (Acipenser oxyrinchus oxyrinchus) and Optimization of Culture Conditions Aquatic Biology, DOI 10.3354/ab0383
Richter A., Kruse C., Moser A., Hofmann U. G. and Danner S. Next-generation deep brain stimulating devices with neuropil-mimicking cell cover Regenerative Medicine 6, 463, ISSN 1746-0751

Publikationen 2010#


Autor Titel Verlag
Ernst N., Tiede S., Tronnier V., Kruse C., Zechel C., Paus R. An improved, standardised protocol for the isolation, enrichment and targeted neural differentiation of Nestin+ progenitors from adult human dermis Exp Dermatol. 2010 Jun;19(6):549-55
Rakers S., Gebert M., Uppalapati S., Meyer W., Maderson P., Sell A., Kruse C., Paus R. “Fishy matters”: The relevance of fish skin biology to investigative dermatology Experimental Dermatology, 2010, Apr;19(4):313-24. DOI:10.1111/j.1600-0625.2009.01059.x
Grunow B., Wenzel J., Gebert M., Kruse C. In vitro generated autonomously contracting cardiomyocytes from rainbow trout as a model system for human heart research. Journal of Biotechnology (2010) 150 (1), 6-7
Grunow B., Ciba P., Rakers S., Klinger M., Anders E., Kruse C. In vitro expansion of autonomously contracting, cardiomyogenic structures from rainbow trout, Oncorhynchus mykiss. Journal of fish biology (2010) 76, 427-434
Ciba P., Hering-Hagenbeck S., Nagel U., Kruse C. Untersuchung und Archivierung von Stammzellen aus Wildtieren; hier: Schneeleopard (Uncia uncia) und Rothschildgiraffe (Giraffa camelopardalis rothschildi). Der Zoologische Garten. 10.1016/j.zoolgart.2010.08.001
Richter A., Kruse C., Hofmann U.G., Danner S. Applying controlled shear stress on cell covered microprobes Biomedizinische Technik/Biomedical Engineering - de Gruyter (2010) 55, 4, ISSN: 0939-4990
Petschnik A. E., Fell B., Klatte J. E., Evers L. H., Kruse C., Danner S. Humane Schweißdrüsen: eine viel versprechende Quelle für Nestin-positive Stammzellen Regenerative Medizin, 3. Jahrgang, Heft 1, S. 8-9
Petschnik A. E, Fell B., Kruse C., Danner S. The role of alpha-smooth muscle actin in myogenic differentiation of human glandular stem cells and their potential for smooth muscle cell replacement therapies Expert Opin Biol Ther, Jun;10(6):853-61
Petschnik A. E., Klatte J. E., Evers L. H., Kruse C., Paus R., Danner S. Phenotypic indications that human sweat glands are a rich source of nestin-positive stem cell populations Br J Dermatol, 162(2):380-3
Luellwitz L., Hoffmann D., Grunow B., Noglick S., Gebert M., Kruse C. A novel fish cell line converts n-3 polyunsaturated fatty acids into n-3 highly unsaturated fatty acids in vitro Abstracts of the First International Marine Ingredients Conference Oslo, Oslo, Norway

Publikationen 2009#


Autor Titel Verlag
Ciba P., Danner S. Neue Haut aus Stammzellen Labor and More, 5/2009
Salem H., Ciba P., Rapoport D. H., Egana J. T., Reithmayer K., Kadry M., Machens H. G., Kruse C. The influence of pancreas-derived stem cells on scaffold based skin regeneration Biomaterials, 2009 Feb;30(5):789-96
Grunow B., Gebert M., Kruse C. Heart Regeneration versus Heart Development. Regenerative Medicine, Nov 4 (6), 187 2
Richter A., Loeffler S., Moser A., Kruse C., Hofmann U., Danner S. Improvement of neural prosthetic devices using adult pancreatic stem cells Biomaterialien (2009) 10, 104; ISSN:1616-0177
Richter A., Kruse C., Hofmann U., and Danner S. Cell-based improvement of neural prosthetic device - BioStar 2008–Science in Exchange Meeting Abstracts Tissue Engineering Part A (2009) 15, 675-737, DOI:10.1089/ten.tea.2009.1500
Petschnik A. E., Ciba P., Kruse C., Danner S. Controlling alpha-SMA expression in adult human pancreatic stem cells by soluble factors Ann Anat, 191, 116-125
Egana J. T., Danner S., Kremer M., Rapoport D. H., Lohmeyer J. A., Dye J. F., Hopfner U., Lavandero S., Kruse C., Machens H. G. The use of glandular-derived stem cells to improve vascularization in scaffold-mediated dermal regeneration Biomaterials 30:446-58
Lermen D., Blömeke B., Browne R., Clarke A., Dyce P. W., Fixemer T., Fuhr G.R., Holt W. V., Jewgenow K., Llloyd R.E., Lötters S., Paulus M., Reid G., Rapoport D. H., Rawson D., Ringleb J., Ryder O. A., Spörl G., Schmitt T., Veith M., Müller P. Cryobanking of viable biomaterials: implementation of new strategies for Conservation purposes Molecular Ecology; 18, 1030-1033

Publikationen 2008#


Autor Titel Verlag
Ciba P., Sturmheit T. M., Petschnik A. E., Kruse C., Danner S. In vitro cultures of human pancreatic stem cells: Gene and protein expression of designated markers varies with passage Annals of anatomy 191 (2009) 94—103
Kruse C., Danner S., Rapoport D. H., Current Stem Cell Technology: Limitations and Realistic Expectations Eng. Life Sci.
Ciba, P., Schicktanz, S., Anders, E., Siegl, E., Stielow, A., Klink, E., Kruse, C. Long-Term Culture of a Cell Population from Siberian Sturgeon (Acipenser Baerii) Head Kidney. Fish Physiology and Biochemistry,Vol 34, Number 4 (2008), 367-372; IF: 0,505
Kruse, C., Danner, S., Rapoport, D. Current Stem Cell Technology: Limitations and Realistic Expectations. Eng.Life Sci. 8, No. 1, 13–18 (2008)
Kajahn, J., Gorjup, E., Tiede, S., v. Briesen, H., Paus, R., Kruse, C and Danner, S. Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. Eur. J. Cell Biol. (2008) 87:39-46. Epub 2007 Sep 1

Publikationen 2007#


Autor Titel Verlag
Ciba P., Schicktanz S., Anders E., Siegl E., Stielow A., Klink E., Kruse C. Long-term culture of a cell population from Siberian sturgeon (Acipenser baerii ) head kidney. Fish physiology and biochemistry (2007) DOI 10.1007/s10695-007-9196-8
Danner, S., Kajahn, J., Geismann, C., Klink, E. and Kruse, C. Derivation of oocyte-like cells from a clonal pancreatic stem cell line. Mol. Hum. Reprod, (2007); 13:11-20. Epub 2006 Nov 17
Tiede, S., Kloepper, J.E., Bodò, E, Tiwari, S., Kruse, C. and Paus, R. Hair follicle stem cells: Walking the maze. Eur. J. Cell Biol. (2007) 86:355-376. Epub 2007 Jun 18
Hilgendorf, I., Aßmuth, K., Sparmann, G.,Emmrich, J. and Kruse, C. Enhanced vigilin and anionic trypsinogen expression in experimental chronic pancreatitis. Centr. Eur. J. Med . (2007) 2:159-167

Publikationen 2006#


Autor Titel Verlag
Kruse C., Bodó E., Petschnik A. E., Danner S., Tiede S., Paus R. Towards the development of a pragmatic technique for isolating and differentiating nestin-positive cells from human scalp skin into neuronal and glial cell populations: generating neurons from human skin? Exp Dermatol, 15, 794-800
Kruse C., Kajahn J., Petschnik A. E., Maass A., Klink E., Rapoport D. H., Wedel T. Adult pancreatic stem/progenitor cells spontaneously differentiate in vitro into multiple cell lineages and form teratoma-like structures Ann Anat, 188, 503-517
Guldner N. W., Kajahn J., Klinger M., Sievers H.-H., Kruse, C. Autonomously contracting human cardiomyocytes generated from adult pancreatic stem cells and enhanced in cocultures with myocardial biopsies. Artif. Org. 29 (2006), 1158-1166
Kruse C., Klink E., Kajahn J., Wedel T., Danner S. Pancreatic stem cells form multicellular teratoma-like structures in vitro. Cytotherapy 8 (2006), 50
Danner S. and Kruse C. Clonal analysis of long-term cultures from pancreatic stem cells. Cytotherapy 8 (2006), 50
Kajahn J., Ciba P., Klinger M., Kruse C., Guldner N. W. Human cardiomyogenic cells generated from adult human pancreatic stem cells. Cytotherapy 8 (2006), 50
Kruse C. Möglichkeiten und Grenzen der Stammzelltherapie. in: „Technische Systeme für Biotechnologie und Umwelt“, 9-12, Hrsg.: Dieter Beckmann und Manfred Meister; ISBN-10: 3-00-018621-2 (2006)

Publikationen 2005#


Autor Titel Verlag
Kramer, J., Klinger, M., Kruse, C., Faza, M., Hargus, G., Rohwedel, J. Ultrastructural analysis of mouse embryonic stem cell-derived chondrocytes. Anat. Embryol. (Berl.) 210 (2005), 175‑185
Maass, A., Rohwedel, J., Wedel, T. and Kruse, C. Characterization of adult stem cells derived from rat pancreas. Int. J. Artif. Organs 28 (2005), 397

Publikationen 2004#


Autor Titel Verlag
Vollbrandt, T., Willkomm, D., Stoßberg, H., and Kruse, C. Vigilin is colocalized with 80S ribosomes and binds to the ribosomal complex through its C-terminal domain. Int. J. Biochem. Cell Biol. 36 (2004), 1306-1318
Kruse, C., Birth, M., Rohwedel, J., Assmuth, K., Goepel, A., and Wedel, T. Pluripotency of adult stem cells derived from human and rat pancreas. Appl. Phys. A 79 (2004), 1617-1624